OBO ID: DOID:0081083
Term Name: acute myeloid leukemia with inv(3) (q21.3;q26.2) or t(3;3) (q21.3;q26.2) Search Ontology:
Synonyms:
  • Acute Myeloid Leukemia with inv(3) (q21.3;q26.2) or t(3;3) (q21.3;q26.2); GATA2, MECOM
  • Acute myeloid leukemia with inv(3)(q21;q26.2) or t(3;3)(q21;q26.2); RPN1-EVI1
Definition: An acute myeloid leukemia associated with inv(3)(q21q26.2) or t(3;3)(q21;q26.2), resulting in the expression of RPN1-EVI1 fusion protein and the reposition of a distal GATA2 enhancer to activate MECOM expression. https://pubmed.ncbi.nlm.nih.gov/31711889/
References:
  • ICDO:9869/3
  • NCI:C82426
  • SNOMEDCT_US_2022_03_01:780844005
  • UMLS_CUI:C2826172
Ontology: Human Disease   (DOID:0081083)
OTHER acute myeloid leukemia with inv(3) (q21.3;q26.2) or t(3;3) (q21.3;q26.2) PAGES
GENES INVOLVED No data available
ZEBRAFISH MODELS No data available
PHENOTYPE No data available

CITATIONS: None