Term Name: |
ketotifen |
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Search Ontology:
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Synonyms: |
- 10-(1-methyl-4-piperidinylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one
- 4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one
- ketotifen
- ketotifene
- ketotifeno
- ketotifenum
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Definition: |
An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
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References: |
- CAS:34580-13-7
- DrugBank:DB00920
- Drug_Central:1530
- HMDB:HMDB0015056
- KEGG:D08105
- LINCS:LSM-2637
- Patent:DE2111071
- Patent:US3682930
- Wikipedia:Ketotifen
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Ontology: |
ChEBI
(
EBI
)
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