OBO ID: CHEBI:90926
Term Name: tenofovir alafenamide Search Ontology:
Synonyms:
  • GS 7340
  • GS-7340
  • propan-2-yl N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate
  • TAF
  • tenofovir alafenamide
Definition: An L-alanine derivative that is isopropyl L-alaninate in which one of the amino hydrogens is replaced by an (S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl group. A prodrug for tenofovir, it is used (as the fumarate salt) in combination therapy for the treatment of HIV-1 infection.
References:
Ontology: Chebi
PHENOTYPE No data available