OBO ID: CHEBI:68647

Term Name:	regorafenib		Search Ontology:
Synonyms:	4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide BAY 73-4506 regorafenib regorafenibum
Definition:	A pyridinecarboxamide obtained by condensation of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]pyridine-2-carboxylic acid with methylamine. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy.
References:	CAS:755037-03-7 Drug_Central:4654 KEGG:D10138 LINCS:LSM-1226 PMID:21170960 PMID:21419931 PMID:21752724 PMID:22421192 PMID:22568966 PMID:22577890 PMID:22612461 PMID:22614970 PMID:22706543 PMID:22777740 PMID:22785409 PMID:22959186 Patent:US2006058358 Patent:WO2006125540 Patent:WO2007054216 Patent:WO2007068380 Patent:WO2007068382 Patent:WO2008043446 Patent:WO2008055629 Patent:WO2008058644 Patent:WO2008089388 Patent:WO2008089389 Patent:WO2011128261 Patent:WO2011130728 Reaxys:14359949 Wikipedia:Regorafenib
Ontology:	ChEBI  ( EBI )