OBO ID: CHEBI:6427

Term Name:	leuprolide		Search Ontology:
Synonyms:	(D-Leu(6),des-Gly-NH2(10),Pro-ethylamide(9))-gonadotropin-releasing hormone 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamide Leuprorelin leuprorelina leuproreline leuprorelinum pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHC2H5 pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt
Definition:	An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-leucyl, leucyl, arginyl, and N-ethylprolinamide residues joined in sequence. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant (particularly as the acetate salt) for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.
References:	CAS:53714-56-0 DrugBank:DB00007 Drug_Central:1559 KEGG:C07612 KEGG:D08113 Patent:DE2446005 Patent:US4005063 Reaxys:741818
Ontology:	ChEBI  ( EBI )