- 8-Br-Cyclic GMP
- 8-Bromocyclic GMP
- 8-Bromocyclic guanosine monophosphate
- 8-bromoguanosine 3',5'-(hydrogen phosphate)
- 8-Bromoguanosine 3',5'-cyclic monophosphate
- 8-Bromoguanosine 3',5'-monophosphate
||A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP bearing an additional bromo substituent at position 8 on the guanine ring. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.