OBO ID: CHEBI:64108
Term Name: 8-bromo-3',5'-cyclic GMP Search Ontology:
Synonyms:
  • 8-Br-cGMP
  • 8-Br-Cyclic GMP
  • 8-Bromo-cgmp
  • 8-Bromocyclic GMP
  • 8-Bromocyclic guanosine monophosphate
  • 8-bromoguanosine 3',5'-(hydrogen phosphate)
  • 8-Bromoguanosine 3',5'-cyclic monophosphate
  • 8-Bromoguanosine 3',5'-monophosphate
Definition: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP bearing an additional bromo substituent at position 8 on the guanine ring. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.
References:
Ontology: Chebi
PHENOTYPE No data available