OBO ID: CHEBI:60782

Term Name:	fluprostenol		Search Ontology:
Synonyms:	EINECS 255-029-3 fluprostenol fluprostenolum ICI 81,008 rac-(5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoic acid travoprost acid travoprost free acid
Definition:	An organofluorine compound that is racemic prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of its isopropyl ester prodrug, travoprost, are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. The isopropyl ester group of travoprost is hydrolysed to the biologically active free acid by esterases in the cornea.
References:	CAS:40666-16-8 PMID:11832489 PMID:11929662 PMID:550147 PMID:6090118 PMID:6911921 PMID:6916556 PMID:941381 PMID:951924 Reaxys:8368795
Ontology:	ChEBI  ( EBI )