OBO ID: CHEBI:567361

Term Name:	cladribine		Search Ontology:
Synonyms:	(2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol 2-CdA 2-chloro-2'-deoxy-beta-adenosine 2-chloro-2'-deoxyadenosine 2-chloro-6-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl)purine 2-chloro-deoxyadenosine 2-chlorodeoxyadenosine 2ClAdo cladribina Cladribine cladribinum CldAdo
Definition:	2'-Deoxyadenosine in which the hydrogen at position 2 on the purine ring has been substituted by chlorine. It inhibits the synthesis and repair of DNA, particularly in lymphocytes and monocytes, and is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including hairy-cell leukaemia and chronic lymphocytic leukaemia.
References:	Beilstein:624220 CAS:4291-63-8 DrugBank:DB00242 Drug_Central:667 KEGG:D01370 LINCS:LSM-5976 PMID:17526755 PMID:18570408 PMID:26024233 Patent:EP173059 Patent:US4760137 Wikipedia:Cladribine
Ontology:	ChEBI  ( EBI )