OBO ID: CHEBI:251408
Term Name: edrophonium Search Ontology:
  • (3-hydroxyphenyl)dimethylethylammonium
  • 3-hydroxy-N,N-dimethyl-N-ethylanilinium
  • edrophonium
  • Ethyl-(3-hydroxy-phenyl)-dimethyl-ammonium
  • N-ethyl-3-hydroxy-N,N-dimethylanilinium
  • N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium
Definition: A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
  • Beilstein:3905622
  • CAS:312-48-1
  • DrugBank:DB01010
  • Drug_Central:988
  • KEGG:C06976
  • LINCS:LSM-5867
  • PDBeChem:EDR
  • PMID:7488499
Ontology: Chebi
PHENOTYPE No data available