OBO ID: CHEBI:166872
Term Name: nucleocidin Search Ontology:
Synonyms:
  • 4'-C-fluoroadenosine 5'-sulfamate
  • 4'-fluoro-5'-O-sulfamoyladenosine
  • 4'-fluoro-5'-O-sulphamoyladenosine
  • [(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-fluoro-3,4-dihydroxyoxolan-2-yl]methyl sulfamate
  • [(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-fluoro-3,4-dihydroxytetrahydrofuran-2-yl]methyl sulfamate
  • [(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-2-fluoro-3,4-dihydroxyoxolan-2-yl]methyl sulfamate
  • antibiotic T-3018
  • T-3018
Definition: A nucleoside antibiotic that is 5'-O-sulfamoyladenosine in which the hydrogen atom at position 4' is replaced by a fluorine atom. It is a natural product synthesized by several Streptomyces species. It exhibits broad spectrum antibacterial activity, and also has a strong effect against Trypanosoma brucei, the protozoan parasite responsible for the African sleeping sickness.
References:
Ontology: Chebi
PHENOTYPE No data available