Gene
nipsnap1
- ID
- ZDB-GENE-991008-17
- Name
- nipsnap homolog 1 (C. elegans)
- Symbol
- nipsnap1 Nomenclature History
- Previous Names
-
- zgc:153339
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable protein-macromolecule adaptor activity. Involved in mitophagy. Predicted to be active in mitochondrial matrix. Is expressed in several structures, including endoderm; heart; liver; pectoral fin; and pleuroperitoneal region. Used to study Parkinson's disease. Orthologous to human NIPSNAP1 (nipsnap homolog 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Princely Abudu et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Princely Abudu et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Parkinson's disease | uio1Tg + CRISPR1-nipsnap1 + CRISPR2-nipsnap1 + CRISPR3-nipsnap1 | standard conditions | Princely Abudu et al., 2019 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Dimeric alpha-beta barrel | NIPSNAP | NipSnap domain-containing protein |
|---|---|---|---|---|
|
UniProtKB:F6NVH9
|
279 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nipsnap1-201
(1)
|
Ensembl | 1,472 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-nipsnap1 | polyclonal | IgG | Rabbit |
|
Abcam plc
|
2 |
Plasmids
No data available