Gene
gsk3ab
- ID
- ZDB-GENE-990714-3
- Name
- glycogen synthase kinase 3 alpha b
- Symbol
- gsk3ab Nomenclature History
- Previous Names
-
- GSK-3[a] (1)
- gsk3a
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Involved in cardiac muscle cell development; dorsal/ventral pattern formation; and heart looping. Predicted to localize to axon; cytosol; and nucleus. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human GSK3A (glycogen synthase kinase 3 alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR039192 | Glycogen synthase kinase 3, catalytic domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Glycogen synthase kinase 3, catalytic domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|
|
UniProtKB:Q9YH61
|
440 | |||||
|
UniProtKB:A0A8M3AQC2
|
435 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| aberrant processed transcript |
gsk3ab-203
(1)
|
Havana | 576 nt | |
| mRNA |
gsk3ab-201
(1)
|
Havana | 2971 nt | |
| ncRNA |
gsk3ab-003
(1)
|
Havana | 901 nt |
Interactions and Pathways
No data available
Plasmids
No data available