Gene
wif1
- ID
- ZDB-GENE-990712-17
- Name
- wnt inhibitory factor 1
- Symbol
- wif1 Nomenclature History
- Previous Names
-
- zgc:110507 (1)
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have signaling receptor binding activity. Involved in negative regulation of canonical Wnt signaling pathway and swim bladder development. Predicted to localize to cell surface and extracellular region. Human ortholog(s) of this gene implicated in breast cancer; renal cell carcinoma; and urinary bladder cancer. Is expressed in several structures, including anterior swim bladder bud; nervous system; paraxial mesoderm; pharyngeal arch; and pleuroperitoneal region. Orthologous to human WIF1 (WNT inhibitory factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu316 (19 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Developmental Signaling Modulators | EGF-like, conserved site | EGF-like domain | WIF domain | WIF domain superfamily | Wnt inhibitory factor (WIF)-1 |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9W6F9
|
378 |
Interactions and Pathways
No data available
Plasmids
No data available