Gene
dtymk
- ID
- ZDB-GENE-990603-11
- Name
- deoxythymidylate kinase (thymidylate kinase)
- Symbol
- dtymk Nomenclature History
- Previous Names
-
- tymk
- wu:fa12c02
- wu:fb14h07
- wu:ft84f02
- zgc:123174
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable dTMP kinase activity and nucleoside diphosphate kinase activity. Acts upstream of or within DNA repair and central nervous system neuron development. Predicted to be active in mitochondrion and nucleus. Orthologous to human DTYMK (deoxythymidylate kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Vanoevelen et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodegeneration, childhood-onset, with progressive microcephaly | 619847 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Thymidylate kinase | Thymidylate kinase, conserved site | Thymidylate kinase-like domain |
|---|---|---|---|---|---|
|
UniProtKB:Q3B752
|
212 |
Interactions and Pathways
No data available
Plasmids
No data available