Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-98
Gene Name: homeobox A2b
Gene Symbol: hoxa2b
Previous Names: hoxa2, etID309949.16 (1), Z-75
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 38 figures from 29 publications
Directly Submitted Expression Data: 6 figures (16 images) from Thisse et al., 2005 [eu715]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  hindbrain, hindbrain neural plate, hyoid neural crest, neural crest (all 25) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-hoxa2b (2)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
?Microtia with or without hearing impairment (AD) 612290
?Microtia, hearing impairment, and cleft palate (AR) 612290
GENE ONTOLOGY
Ontology GO Term
Biological Process multicellular organismal development (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR001827 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00032 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hoxa2b-001 (1) 1914
    ottdart00000001850 (1) 1797
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM hoxa2b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    hoxa2b Contained in: [BAC] DKEY-45E15 (1)
    [PAC] BUSM1-31B14 (1) (order this)
    hoxa2b Encodes: [EST] eu715 (1)
    [cDNA] MGC:193940 (1) (order this), MGC:193947 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131106 (1) 1797 bp
    Genomic GenBank:CR392024 (1) 183486 bp
    Select Tool
    Polypeptide UniProtKB:B3DG99 (1) 363 aa
    Sequence Clusters UniGene:82597 (1)
    Sequence Information (all 30)
    OTHER hoxa2b GENE PAGES
  • Gene:30325 (1)
  • VEGA:OTTDARG00000001732 (1)
  • VEGA:OTTDARG00000027661 (1)
  • Ensembl(Zv9):ENSDARG00000023031 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish hoxa2b 16  
    Human HOXA2 7 (7p15.2)
  • OMIM:604685
  • Gene:3199
  • Mouse Hoxa2 6 ( 25.40 cM)
  • MGI:96174
  • Gene:15399
  • Orthology Details
    CITATIONS (77)