ZFIN ID: ZDB-GENE-990415-98
Gene Name: homeobox A2b
Gene Symbol: hoxa2b

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: hoxa2, etID309949.16 (1), Z-75

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 40 figures from 31 publications
Directly Submitted Expression Data: 6 figures (16 images) from Thisse et al., 2005 [eu715]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  hindbrain, hindbrain neural plate, hyoid neural crest, neural crest (all 29) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa36100 Point Mutation Unknown Splice Site ENU
Targeting reagents: MO1-hoxa2b (2), MO2-hoxa2b (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH hoxa2b HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
?Microtia with or without hearing impairment (AD) 612290
?Microtia, hearing impairment, and cleft palate (AR) 612290
GENE ONTOLOGY
Ontology GO Term
Biological Process multicellular organism development (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR001827 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00032 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hoxa2b-001 (1) 1914
    ottdart00000001850 (1) 1797
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM hoxa2b
    Tg(hoxa2b:EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    hoxa2bContained in: [BAC] DKEY-45E15 (1) (order this)
    [PAC] BUSM1-31B14 (1) (order this)
    hoxa2bEncodes: [EST] eu715 (1)
    [cDNA] MGC:193940 (1) (order this), MGC:193947 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131106 (1) 1797bp
    Genomic GenBank:CR392024 (1) 183486bp
    Select Tool
    Polypeptide UniProtKB:B3DG99 (1) 363aa
    Sequence Clusters UniGene:82597 (1)
    Sequence Information (all 28)
    OTHER hoxa2b GENE PAGES
  • Gene:30325 (1)
  • VEGA:OTTDARG00000001732 (1)
  • VEGA:OTTDARG00000027661 (1)
  • Ensembl(GRCz10):ENSDARG00000023031 (1)
  • ORTHOLOGY for hoxa2b (Chr: 16)
    Species Symbol Chromosome Accession # Evidence
    Human HOXA2 7
  • Gene:3199
  • OMIM:604685
  • HGNC:5103
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (2)
    Mouse Hoxa2 6
  • MGI:96174
  • Gene:15399
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (2)
    Download Curated Orthology
    CITATIONS (85)