Gene
hoxa11b
- ID
- ZDB-GENE-990415-4
- Name
- homeobox A11b
- Symbol
- hoxa11b Nomenclature History
- Previous Names
-
- Hoxa-11
- hoxa11
- im:7142641
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure development and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; chondroblast; mesenchyme; pectoral fin bud; and pectoral fin field. Human ortholog(s) of this gene implicated in radioulnar synostosis. Orthologous to human HOXA11 (homeobox A11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7142641 (1 image)
- eu331 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Radioulnar synostosis with amegakaryocytic thrombocytopenia 1 | 605432 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Domain of unknown function DUF3528, homeobox protein, eukaryotic | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|
|
UniProtKB:Q9DDU1
|
283 | |||||
|
UniProtKB:B3DHW9
|
283 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hoxa11b-201
(1)
|
Ensembl | 1,878 nt |
Interactions and Pathways
No data available
Plasmids