| ZFIN ID: ZDB-GENE-990415-238 |
| Gene Name: | retinal homeobox gene 3 |
|---|---|
| Gene Symbol: | rx3 |
| Previous Names: | chk, chokh, eyes missing (1), eym (1) |
| All Expression Data: | 46 figures from 30 publications |
| Wild-type Stages, Structures: | Gastrula:Shield (6.0h-8.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) |
|---|---|
anterior neural plate,
diencephalon,
forebrain,
forebrain ventral region
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| Curated Microarray Expression: | GEO (1) |
| Mutant lines: | 12 genotypes |
| Alleles: |
hu499,
ne2611,
rx3_unspecified,
s399,
t25181
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| Knockdown reagents: | MO1-rx3 (1), MO2-rx3 (1), MO3-rx3 (1) |
| Data: | 12 figures from 6 publications |
| Observed in: |
adenohypophysis,
adenohypophysis development,
camera-type eye morphogenesis,
ethmoid cartilage
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| Phenotype of Human Orthologue | OMIM Phenotype ID |
|---|---|
| Microphthalmia, isolated 3 | 611038 |
| Ontology | GO Term |
|---|---|
| Biological Process | adenohypophysis development (more) |
| Cellular Component | nucleus (more) |
| Molecular Function | DNA binding (more) |
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| rx3 Contained in: | [BAC] CH211-233A1 (1) (order this) |
| rx3 Encodes: | [cDNA] MGC:195183 (1), MGC:195186 (1) |
| Type | Accession # | Length (bp/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_131227 (1) | 1322 bp |
Select Tool
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| Genomic | GenBank:BX248399 (1) | 158884 bp | |
| Polypeptide | UniProtKB:O42358 (1) | 292 aa |
Select Tool
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| Sequence Clusters | UniGene:540 (1) |
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| Chr: 21 Details | View Map: Merged Individual Panels |
| Evidence | ||||||
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| Species | Symbol | Chromosome (Position) | Accession # | AA | CL | |
| Zebrafish | rx3 | 21 |
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| Human | RAX | 18 (18q21.32) |
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| Mouse | Rax | 18 ( 39.03) |
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