Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-524
Gene Name: wingless-type MMTV integration site family, member 10b
Gene Symbol: wnt10b
Previous Names: wnt-d (1), wnt10br, wnt[d], Zwnt[d]
GENE EXPRESSION
All Expression Data: 11 figures from 6 publications
Directly Submitted Expression Data: 6 figures (18 images) from Thisse et al., 2005 [eu346]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Long-pec (48.0h-60.0h)
  hindbrain, midbrain, midbrain hindbrain boundary, neural plate (all 9) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 3 genotypes
Alleles: w5
Knockdown reagents: MO1-wnt10b (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Split-hand/foot malformation 6 225300
GENE ONTOLOGY
Ontology GO Term
Biological Process midbrain-hindbrain boundary development (more)
Cellular Component extracellular region (more)
Molecular Function receptor binding (more)
GO Terms (all 26)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005817 (1)
  • InterPro:IPR013302 (1)
  • InterPro:IPR018161 (1)
  • PROSITE:PS00246 (1)
  • Pfam:PF00110 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA wnt10b-001 (1) 1515
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM wnt10b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    wnt10b Contained in: [BAC] DKEY-166N8 (1) (order this)
    wnt10b Encodes: [EST] eu346 (1)
    [cDNA] MGC:193879 (1) (order this), MGC:193917 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_178219 (1) 1492 bp
    Genomic GenBank:CR352210 (1) 180924 bp
    Select Tool
    Polypeptide UniProtKB:Q801F7 (1) 427 aa
    Sequence Clusters UniGene:88562 (1)
    Sequence Information (all 17)
    OTHER wnt10b GENE PAGES
  • Gene:30308 (1)
  • VEGA:OTTDARG00000021308 (1)
  • Ensembl(Zv9):ENSDARG00000040925 (1)
  • MAPPING INFORMATION
    Chr: 23 Details View Map: Merged   Individual Panels
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish wnt10b 23  
    Human WNT10B 12 (12q13)
  • OMIM:601906
  • Gene:7480
  • Mouse Wnt10b 15 ( 54.65)
  • MGI:108061
  • Gene:22410
  • CITATIONS (35)