Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-512
Gene Name: neural adhesion molecule L1.1
Gene Symbol: nadl1.1
Previous Name: wu:fa30h05
Nomenclature History
GENE EXPRESSION
All Expression Data: 16 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2008 [cssl:d824]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  diencephalon, dorsal root ganglion, hindbrain neuron, magnocellular octaval nucleus (all 15) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 1 genotype
Alleles: sa12283, sa756
Knockdown reagents: MO1-nadl1.1 (1), MO2-nadl1.1 (1)
PHENOTYPE
Data: 2 figures from 2 publications
Observed in: axonal fasciculation, ceratohyal cartilage, hyosymplectic cartilage, interhyal cartilage (all 8) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Corpus callosum, partial agenesis of 304100
CRASH syndrome 303350
Hydrocephalus due to aqueductal stenosis 307000
Hydrocephalus with congenital idiopathic intestinal pseudoobstruction 307000
Hydrocephalus with Hirschsprung disease 307000
MASA syndrome 303350
GENE ONTOLOGY
Ontology GO Term
Biological Process axon regeneration (more)
Cellular Component integral component of membrane (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003598 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR003961 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR026966 (1)
  • PROSITE:PS50835 (1)
  • PROSITE:PS50853 (1)
  • Pfam:PF00041 (1)
  • Pfam:PF07679 (1)
  • Pfam:PF13882 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nadl1.1-001 (1) 4529
    ncRNA nadl1.1-002 (1) 405
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM nadl1.1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nadl1.1 Contained in: [BAC] DKEYP-44B8 (1)
    nadl1.1 Encodes: [EST] fa30h05 (1)
    [cDNA] cssl:d824 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131383 (1) 4052 bp
    Genomic GenBank:BX323461 (1) 169310 bp
    Select Tool
    Polypeptide UniProtKB:F1R5A9 (1) 1332 aa
    Sequence Clusters UniGene:75066 (1)
    Sequence Information (all 25)
    OTHER nadl1.1 GENE PAGES
  • Gene:30656 (1)
  • VEGA:OTTDARG00000021065 (1)
  • Ensembl(Zv9):ENSDARG00000015025 (1)
  • MAPPING INFORMATION
    Chr: 23 Details View Map: Merged   Individual Panels
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA NS
    Zebrafish nadl1.1 23  
    Human L1CAM X (Xq28)
  • OMIM:308840
  • Gene:3897
  • Mouse L1cam X ( 37.43 cM)
  • MGI:96721
  • Gene:16728
  • CITATIONS (31)