ZFIN ID: ZDB-GENE-980526-512
Gene Name: neural adhesion molecule L1.1
Gene Symbol: nadl1.1
Previous Name: wu:fa30h05
Location: Chr: 23   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 16 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2008 [cssl:d824]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  diencephalon, dorsal root ganglion, enteric nervous system, hindbrain neuron (all 16) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: nadl1.1sa756/sa756(Tupfel long fin)
Knockdown reagents: MO1-nadl1.1 (1), MO2-nadl1.1 (1)

Allele Type Mutagen Suppliers
sa756 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12283 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in: axonal fasciculation, ceratohyal cartilage, hyosymplectic cartilage, interhyal cartilage (all 8) expand
    DISEASE ASSOCIATED WITH nadl1.1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    MASA syndrome CRASH syndrome 303350
    hydrocephalus Hydrocephalus due to aqueductal stenosis 307000
    Hydrocephalus with congenital idiopathic intestinal pseudoobstruction 307000
    Hydrocephalus with Hirschsprung disease 307000
    MASA syndrome MASA syndrome 303350
    Corpus callosum, partial agenesis of 304100
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cartilage morphogenesis (more)
    Cellular Component axonal growth cone (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003598 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR003961 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR026965 (1)
  • InterPro:IPR026966 (1)
  • PROSITE:PS50835 (1)
  • PROSITE:PS50853 (1)
  • Pfam:PF00041 (1)
  • Pfam:PF07679 (1)
  • Pfam:PF13882 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nadl1.1-001 (1) 4529
    ncRNA nadl1.1-002 (1) 405
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nadl1.1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nadl1.1 Contained in: [BAC] DKEYP-44B8 (1)
    nadl1.1 Encodes: [EST] fa30h05 (1)
    [cDNA] cssl:d824 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131383 (1) 4052 bp
    Genomic GenBank:BX323461 (1) 169310 bp
    Select Tool
    Polypeptide UniProtKB:F1R5A9 (1) 1332 aa
    Sequence Clusters UniGene:75066 (1)
    Sequence Information (all 21)
    OTHER nadl1.1 GENE PAGES
  • Gene:30656 (1)
  • VEGA:OTTDARG00000021065 (1)
  • Ensembl(Zv9):ENSDARG00000015025 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA NS
    Zebrafish nadl1.1 23  
    Human L1CAM X (Xq28)
  • OMIM:308840
  • Gene:3897
  • Mouse L1cam X ( 37.43 cM)
  • MGI:96721
  • Gene:16728
  • Orthology Details
    CITATIONS (33)