Gene
dlx2b
- ID
- ZDB-GENE-980526-18
- Name
- distal-less homeobox 2b
- Symbol
- dlx2b Nomenclature History
- Previous Names
-
- dlx5
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including dental epithelium; dental mesenchyme; forebrain; parasphenoid; and splanchnocranium. Orthologous to human DLX2 (distal-less homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 50 figures from 30 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu649 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR000047 | Helix-turn-helix motif |
Conserved_site | IPR017970 | Homeobox, conserved site |
Domain | IPR001356 | Homeodomain |
Domain | IPR020479 | Homeodomain, metazoa |
Domain | IPR022135 | Distal-less-like homeobox protein, N-terminal domain |
Family | IPR050460 | Distal-less homeobox transcription factors |
Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
Domain Details Per Protein
Protein | Length | Distal-less homeobox transcription factors | Distal-less-like homeobox protein, N-terminal domain | Helix-turn-helix motif | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Homeodomain, metazoa |
---|---|---|---|---|---|---|---|---|
UniProtKB:Q98876
|
276 | |||||||
UniProtKB:A4IG28
|
276 |
Interactions and Pathways
No data available
Plasmids
No data available