| ZFIN ID: ZDB-GENE-980526-166 |
| Gene Name: | sonic hedgehog a |
|---|---|
| Gene Symbol: | shha |
| Previous Names: | shh, syu, vhh1 (1), fc83d08, sonic you, sonic-you (1), vertebrate hedgehog homolog (1), wu:fc83d08 (1) |
| Nomenclature History | |
| All Expression Data: | 296 figures from 227 publications |
| Wild-type Stages, Structures: | Blastula:256-cell (2.5h-2.75h) to Adult (90d-730d, breeding adult) |
|---|---|
anterior neural keel,
anterior neural rod,
axial chorda mesoderm,
axial mesoderm
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| Curated Microarray Expression: | GEO (1) |
| Mutant lines: | 35 genotypes |
| Alleles: |
b240,
shha_unspecified,
t4,
tbq70,
tbx392
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| Knockdown reagents: | MO1-shha (1), MO2-shha (1), MO3-shha (1), MO4-shha (1) |
| Data: | 23 figures from 14 publications |
| Observed in: |
adaxial cell,
anatomical system,
blood circulation,
eye
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| Phenotype of Human Orthologue | OMIM Phenotype ID |
|---|---|
| Holoprosencephaly-3 | 142945 |
| Microphthalmia with coloboma 5 | 611638 |
| Schizencephaly | 269160 |
| Single median maxillary central incisor | 147250 |
| Ontology | GO Term |
|---|---|
| Biological Process | adenohypophysis development (more) |
| Cellular Component | extracellular region (more) |
| Molecular Function | hydrolase activity (more) |
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| Type | Name | Length (bp) | Analysis | |||
|---|---|---|---|---|---|---|
| mRNA | shha-001 (1) | 2592 |
Select Tool
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 Withdrawn Transcripts |
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Tg(-2.4shha-A:GFP),
Tg(-2.4shha-AB:GFP),
Tg(-2.4shha-ABC:DsRed),
Tg(-2.4shha-ABC:DsRed.T4),
Tg(-2.4shha-ABC:GFP)
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| shha Contained in: | [BAC] CH211-105D1 (1) (order this), CH211-150E22 (1) (order this) |
| shha Encodes: |
[EST]
fc83d08
[cDNA] MGC:194075 (1) (order this) |
| Type | Accession # | Length (bp/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_131063 (1) | 2600 bp |
Select Tool
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| Genomic | GenBank:CU041319 (1) | 174262 bp | |
| Polypeptide | UniProtKB:Q92008 (1) | 418 aa |
Select Tool
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| Sequence Clusters | UniGene:36074 (1) |
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| Chr: 7 Details | View Map: Merged Individual Panels |
| Evidence | ||||||
|---|---|---|---|---|---|---|
| Species | Symbol | Chromosome (Position) | Accession # | AA | CL | |
| Zebrafish | shha | 7 |
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| Human | SHH | 7 (7q36) |
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| Mouse | Shh | 5 ( 14.39) |
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