Gene
mapk8ip1b
- ID
- ZDB-GENE-170525-1
- Name
- mitogen-activated protein kinase 8 interacting protein 1b
- Symbol
- mapk8ip1b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable JUN kinase binding activity and MAP-kinase scaffold activity. Predicted to be involved in JNK cascade. Predicted to act upstream of or within phosphorylation and regulation of JNK cascade. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1).
- Genome Resources
-
- Alliance (1)
- Gene:100333948 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| type 2 diabetes mellitus | Alliance | {Diabetes mellitus, noninsulin-dependent} | 125853 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | JIP1, SH3 domain | JNK-interacting protein 1 | PH-like domain superfamily | PTB/PI domain | SH3 domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AUR2
|
670 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance