Gene
pik3c2g
- ID
- ZDB-GENE-170327-2
- Name
- phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
- Symbol
- pik3c2g Nomenclature History
- Previous Names
-
- si:cabz01083482.2
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Predicted to be involved in cell migration; intracellular signal transduction; and phosphatidylinositol-3-phosphate biosynthetic process. Predicted to act upstream of or within phosphatidylinositol phosphate biosynthetic process and phosphorylation. Predicted to be active in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PIK3C2G (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018936 | Phosphatidylinositol 3/4-kinase, conserved site |
| Domain | IPR000008 | C2 domain |
| Domain | IPR000403 | Phosphatidylinositol 3-/4-kinase, catalytic domain |
| Domain | IPR001263 | Phosphoinositide 3-kinase, accessory (PIK) domain |
| Domain | IPR001683 | Phox homology |
| Domain | IPR002420 | C2 phosphatidylinositol 3-kinase-type domain |
| Family | IPR015433 | Phosphatidylinositol kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR036871 | PX domain superfamily |
| Homologous_superfamily | IPR036940 | Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily |
| Homologous_superfamily | IPR042236 | Phosphoinositide 3-kinase, accessory (PIK) domain superfamily |
Domain Details Per Protein
| Protein | Length | Armadillo-type fold | C2 domain | C2 domain superfamily | C2 phosphatidylinositol 3-kinase-type domain | Phosphatidylinositol 3-/4-kinase, catalytic domain | Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily | Phosphatidylinositol 3/4-kinase, conserved site | Phosphatidylinositol kinase | Phosphoinositide 3-kinase, accessory (PIK) domain | Phosphoinositide 3-kinase, accessory (PIK) domain superfamily | Phox homology | Protein kinase-like domain superfamily | PX domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0G2L6J0
|
||||||||||||||
|
UniProtKB:A0A8M9PR53
|
887 | |||||||||||||
|
UniProtKB:A0A8M9PMY2
|
856 | |||||||||||||
|
UniProtKB:A0A8M6Z287
|
1284 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pik3c2g-201
(1)
|
Ensembl | 4,766 nt |
Interactions and Pathways
No data available
Plasmids
No data available