Gene
wnk2
- ID
- ZDB-GENE-160114-3
- Name
- WNK lysine deficient protein kinase 2
- Symbol
- wnk2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable potassium channel inhibitor activity and protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction; monoatomic ion homeostasis; and regulation of metal ion transport. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm. Orthologous to human WNK2 (WNK lysine deficient protein kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR024678 | Serine/threonine-protein kinase OSR1/WNK, CCT domain |
| Family | IPR050588 | With No Lysine (K) Ser/Thr Protein Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Serine/threonine-protein kinase OSR1/WNK, CCT domain | With No Lysine (K) Ser/Thr Protein Kinase |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QDR7
|
2247 | |||||
|
UniProtKB:A0A8M9PVM9
|
2154 | |||||
|
UniProtKB:A0A8M9QM37
|
2239 | |||||
|
UniProtKB:A0A8M9QI77
|
2234 | |||||
|
UniProtKB:A0A8M9Q7T8
|
2102 |
Interactions and Pathways
No data available
Plasmids
No data available