Gene
grxcr1a
- ID
- ZDB-GENE-160113-42
- Name
- glutaredoxin and cysteine rich domain containing 1 a
- Symbol
- grxcr1a Nomenclature History
- Previous Names
-
- si:dkey-109l4.6 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have electron transfer activity and protein disulfide oxidoreductase activity. Predicted to be involved in cell redox homeostasis and sensory perception of sound. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 25. Is expressed in hair cell anterior macula. Orthologous to human GRXCR1 (glutaredoxin and cysteine rich domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Blanco-Sánchez et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Blanco-Sánchez et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive nonsyndromic deafness 25 | Alliance | Deafness, autosomal recessive 25 | 613285 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glutaredoxin | Glutaredoxin domain-containing cysteine-rich protein 1 | Thioredoxin-like superfamily |
|---|---|---|---|---|
|
UniProtKB:A0A8M1RRF3
|
302 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
grxcr1a-202
(1)
|
Ensembl | 4,642 nt | ||
| mRNA |
si:dkey-109l4.6-001
(1)
|
Ensembl | 1,002 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-grxcr1a | polyclonal | IgG | Rabbit |
|
Novus Biologicals, LLC
|
2 |
Plasmids
No data available