Gene
kdm5a
- ID
- ZDB-GENE-150114-1
- Name
- lysine demethylase 5A
- Symbol
- kdm5a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to have metal ion binding activity. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in ankylosing spondylitis. Orthologous to human KDM5A (lysine demethylase 5A).
- Genome Resources
-
- Alliance (1)
- Gene:100333310 (1)
- Note
-
this gene corresponds to ENSDARG00000079492
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| El Hayek-Chahrour neurodevelopmental syndrome | 620820 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR001606 | ARID DNA-binding domain |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR003347 | JmjC domain |
| Domain | IPR003349 | JmjN domain |
| Domain | IPR004198 | Zinc finger, C5HC2-type |
| Domain | IPR013637 | Lysine-specific demethylase-like domain |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR047970 | Lysine-specific demethylase 5A, second PHD finger |
| Domain | IPR047972 | Lysine-specific demethylase 5A, third PHD-finger |
| Domain | IPR048615 | Lysine-specific demethylase 5, C-terminal helical domain |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036431 | ARID DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | ARID DNA-binding domain | ARID DNA-binding domain superfamily | JmjC domain | JmjN domain | Lysine-specific demethylase 5A, second PHD finger | Lysine-specific demethylase 5A, third PHD-finger | Lysine-specific demethylase 5, C-terminal helical domain | Lysine-specific demethylase-like domain | Zinc finger, C5HC2-type | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z4S0
|
1663 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance