Gene

lmod1b

ID
ZDB-GENE-141215-22
Name
leiomodin 1b (smooth muscle)
Symbol
lmod1b Nomenclature History
Previous Names
  • si:ch211-137o16.10
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have actin binding activity and tropomyosin binding activity. Predicted to be involved in muscle contraction and pointed-end actin filament capping. Human ortholog(s) of this gene implicated in megacystis-microcolon-intestinal hypoperistalsis syndrome. Orthologous to human LMOD1 (leiomodin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Whitesell et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lmod1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Megacystis-microcolon-intestinal hypoperistalsis syndrome 3 619362
Associated With lmod1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003124 WH2 domain
Family IPR004934 Tropomodulin
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Domain Details Per Protein
Protein Length Leucine-rich repeat domain superfamily Tropomodulin WH2 domain
UniProtKB:A0A8M1Q744 671
UniProtKB:E7F062 671
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lmod1b-201 (1) Ensembl 2,715 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations