Gene
mhc1lca
- ID
- ZDB-GENE-140820-4
- Name
- major histocompatibility complex class I LCA
- Symbol
- mhc1lca Nomenclature History
- Previous Names
-
- sb:eu2458
- si:dkey-225f5.5
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to be involved in immune response. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane and extracellular space. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Orthologous to several human genes including CD1A (CD1a molecule); CD1B (CD1b molecule); and CD1C (CD1c molecule).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu2458 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR003597 | Immunoglobulin C1-set |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR011161 | MHC class I-like antigen recognition-like |
| Family | IPR050208 | Antigen-presenting and immune regulatory MHC class I-related |
| Homologous_superfamily | IPR011162 | MHC classes I/II-like antigen recognition protein |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
| Homologous_superfamily | IPR037055 | MHC class I-like antigen recognition-like superfamily |
Domain Details Per Protein
| Protein | Length | Antigen-presenting and immune regulatory MHC class I-related | Immunoglobulin C1-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | MHC classes I/II-like antigen recognition protein | MHC class I-like antigen recognition-like | MHC class I-like antigen recognition-like superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PDN6
|
356 | |||||||||
|
UniProtKB:A0A0R4IZK4
|
350 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-225f5.5-201
(1)
|
Ensembl | 1,663 nt |
Interactions and Pathways
No data available
Plasmids
No data available