Gene
mhc1uma
- ID
- ZDB-GENE-140820-1
- Name
- major histocompatibility complex class I UMA
- Symbol
- mhc1uma Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to be involved in immune response. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane and extracellular space. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); bone marrow cancer (multiple); eye disease (multiple); and liver disease (multiple). Orthologous to several human genes including MICB (MHC class I polypeptide-related sequence B); AZGP1 (alpha-2-glycoprotein 1, zinc-binding); and HFE (homeostatic iron regulator).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003597 | Immunoglobulin C1-set |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR011161 | MHC class I-like antigen recognition-like |
| Family | IPR050208 | Antigen-presenting and immune regulatory MHC class I-related |
| Homologous_superfamily | IPR011162 | MHC classes I/II-like antigen recognition protein |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
| Homologous_superfamily | IPR037055 | MHC class I-like antigen recognition-like superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Antigen-presenting and immune regulatory MHC class I-related | Immunoglobulin C1-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | MHC classes I/II-like antigen recognition protein | MHC class I-like antigen recognition-like | MHC class I-like antigen recognition-like superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7FAH6 | InterPro | 342 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mhc1uma-201
(1)
|
Ensembl | 1,140 nt | ||
| mRNA |
mhc1uma-202
(1)
|
Ensembl | 1,416 nt | ||
| mRNA |
mhc1uma-203
(1)
|
Ensembl | 1,047 nt | ||
| mRNA |
mhc1uma-204
(1)
|
Ensembl | 804 nt | ||
| mRNA |
mhc1uma-205
(1)
|
Ensembl | 807 nt |
Interactions and Pathways
No data available
Plasmids
No data available