Gene

il1fma

ID
ZDB-GENE-140106-231
Name
interleukin-1 family member A
Symbol
il1fma Nomenclature History
Previous Names
  • IL-1Fm (1)
  • IL-1Ra
  • zmp:0000001271
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable cytokine activity. Predicted to be involved in several processes, including cellular response to lipopolysaccharide; macrophage chemotaxis; and neutrophil activation. Predicted to be located in cytosol and lysosome. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); kidney failure (multiple); lung disease (multiple); and vascular disease (multiple). Orthologous to several human genes including IL1RN (interleukin 1 receptor antagonist); IL36A (interleukin 36 alpha); and IL36B (interleukin 36 beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With il1fma Human Ortholog
No data available
Associated With il1fma Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000975 Interleukin-1 family
Homologous_superfamily IPR008996 Cytokine IL1/FGF
Domain Details Per Protein
Protein Additional Resources Length Cytokine IL1/FGF Interleukin-1 family
UniProtKB:K9K4N1 InterPro 356
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA il1fma-201 (1) Ensembl 1,744 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations