Gene

sipa1

ID
ZDB-GENE-140106-128
Name
signal-induced proliferation-associated 1
Symbol
sipa1 Nomenclature History
Previous Names
  • zmp:0000001168 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have GTPase activator activity. Predicted to be involved in several processes, including actin cytoskeleton reorganization; regulation of GTPase activity; and regulation of dendrite morphogenesis. Predicted to localize to integral component of membrane. Orthologous to human SIPA1 (signal-induced proliferation-associated 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sipa1 Human Ortholog
No data available
Associated With sipa1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000331 Rap/Ran-GAP domain
Domain IPR001478 PDZ domain
Family IPR050989 Rap1/Ran GTPase-activating
Homologous_superfamily IPR035974 Rap/Ran-GAP superfamily
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length PDZ domain PDZ superfamily Rap1/Ran GTPase-activating Rap/Ran-GAP domain Rap/Ran-GAP superfamily
UniProtKB:E7FFF0 1261
UniProtKB:A0A8M9Q976 1274
UniProtKB:A0A8M6YZL4 1219
UniProtKB:A0A8M6Z7Y9 1261
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sipa1-201 (1) Ensembl 3,976 nt
mRNA sipa1-202 (1) Ensembl 1,248 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations