Gene
grem2a
- ID
- ZDB-GENE-131127-498
- Name
- gremlin 2, DAN family BMP antagonist a
- Symbol
- grem2a Nomenclature History
- Previous Names
-
- si:dkey-97l21.2
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable BMP binding activity and receptor ligand activity. Predicted to be involved in animal organ morphogenesis and sequestering of BMP from receptor via BMP binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human GREM2 (gremlin 2, DAN family BMP antagonist).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Tooth agenesis, selective, 9 | 617275 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cystine knot, C-terminal | Cystine-knot cytokine | DAN |
|---|---|---|---|---|
|
UniProtKB:F1R4W0
|
195 | |||
|
UniProtKB:A0A8M9Q6E1
|
195 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
grem2a-201
(1)
|
Ensembl | 2,427 nt |
Interactions and Pathways
No data available
Plasmids
No data available