Gene

ralgapa2

ID
ZDB-GENE-131122-56
Name
Ral GTPase activating protein catalytic subunit alpha 2
Symbol
ralgapa2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to enable GTPase activator activity. Predicted to act upstream of or within positive regulation of GTPase activity and regulation of small GTPase mediated signal transduction. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to human RALGAPA2 (Ral GTPase activating protein catalytic subunit alpha 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa17672Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
sa42984Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With ralgapa2 Human Ortholog
No data available
Associated With ralgapa2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000331 Rap/Ran-GAP domain
Domain IPR046859 Ral GTPase-activating protein subunit alpha/beta, N-terminal domain
Family IPR027107 Tuberin/Ral GTPase-activating protein subunit alpha
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR035974 Rap/Ran-GAP superfamily
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Domain Details Per Protein
Protein Additional Resources Length Armadillo-type fold Ral GTPase-activating protein subunit alpha/beta, N-terminal domain Rap/Ran-GAP domain Rap/Ran-GAP superfamily Tuberin/Ral GTPase-activating protein subunit alpha
UniProtKB:A0A8M9PPM4 InterPro 1983
UniProtKB:A0A2R8QI48 InterPro 2015
UniProtKB:A0A2R8RI29 InterPro 1980
UniProtKB:A0A286YB67 InterPro 1964
UniProtKB:A0A8M9P9L9 InterPro 1984
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 17
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ralgapa2-201 (1)
Ensembl
Ensembl 6,153 nt
ZFIN BLAST
mRNA ralgapa2-202 (1)
Ensembl
Ensembl 7,798 nt
ZFIN BLAST
mRNA ralgapa2-203 (1)
Ensembl
Ensembl 6,093 nt
ZFIN BLAST
mRNA ralgapa2-204 (1)
Ensembl
Ensembl 6,214 nt
ZFIN BLAST
mRNA ralgapa2-205 (1)
Ensembl
Ensembl 6,109 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-196M16ZFIN Curated Data
Contained inBACCH211-276P17ZFIN Curated Data
Contained inBACDKEY-8F9ZFIN Curated Data
Contained inBACDKEY-99G10ZFIN Curated Data
Contained inBACDKEYP-57D12ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_068214619 (1)7958 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:BX248129 (1)217707 nt
MegaBLAST
PolypeptideUniProtKB:A0A2R8QI48 (1)2015 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Species Symbol Chromosome Accession # Evidence
HumanRALGAPA220
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseRalgapa22
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
TSV
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