Gene

vwde

ID

ZDB-GENE-131121-540

Name

von Willebrand factor D and EGF domains

Symbol

vwde Nomenclature History

Previous Names

vwdel (1)
si:dkey-30e9.7
zmp:0000001015

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to enable signaling receptor binding activity. Predicted to be involved in anatomical structure development. Predicted to be active in cell surface and extracellular region. Orthologous to human VWDE (von Willebrand factor D and EGF domains).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With vwde Human Ortholog

No data available

Associated With vwde Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR013032	EGF-like, conserved site
Conserved_site	IPR018097	EGF-like calcium-binding, conserved site
Domain	IPR000742	EGF-like domain
Domain	IPR001846	von Willebrand factor, type D domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR013111	EGF-like domain, extracellular
Family	IPR050969	Developmental Signaling Modulators
PTM	IPR000152	EGF-type aspartate/asparagine hydroxylation site

Domain Details Per Protein

Protein	Length	Developmental Signaling Modulators	EGF-like calcium-binding, conserved site	EGF-like calcium-binding domain	EGF-like, conserved site	EGF-like domain	EGF-like domain, extracellular	EGF-type aspartate/asparagine hydroxylation site	von Willebrand factor, type D domain
UniProtKB:A0A0R4IWA2 InterPro	1721

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	si:dkey-30e9.7-201 (1) Ensembl	Ensembl	5,615 nt	Select Tool ZFIN BLAST
mRNA	si:dkey-30e9.7-202 (1) Ensembl	Ensembl	474 nt	Select Tool ZFIN BLAST
mRNA	si:dkey-30e9.7-203 (1) Ensembl	Ensembl	911 nt	Select Tool ZFIN BLAST
mRNA	si:dkey-30e9.7-204 (1) Ensembl	Ensembl	3,321 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations