Gene
htra4
- ID
- ZDB-GENE-131120-192
- Name
- HtrA serine peptidase 4
- Symbol
- htra4 Nomenclature History
- Previous Names
-
- si:dkey-49o11.4
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable insulin-like growth factor binding activity and serine-type endopeptidase activity. Predicted to be involved in positive regulation of apoptotic process and programmed cell death. Predicted to act upstream of or within proteolysis. Predicted to be located in extracellular region. Orthologous to human HTRA4 (HtrA serine peptidase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000867 | Insulin-like growth factor-binding protein, IGFBP |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR002350 | Kazal domain |
| Domain | IPR041489 | PDZ domain 6 |
| Family | IPR001940 | Peptidase S1C |
| Homologous_superfamily | IPR009003 | Peptidase S1, PA clan |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Homologous_superfamily | IPR036058 | Kazal domain superfamily |
Domain Details Per Protein
| Protein | Length | Growth factor receptor cysteine-rich domain superfamily | Insulin-like growth factor-binding protein, IGFBP | Kazal domain | Kazal domain superfamily | PDZ domain | PDZ domain 6 | PDZ superfamily | Peptidase S1C | Peptidase S1, PA clan |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0A0MPH1
|
459 |
Interactions and Pathways
No data available
Plasmids
No data available