Gene

bcorl1

ID

ZDB-GENE-130530-838

Name

BCL6 corepressor-like 1

Symbol

bcorl1 Nomenclature History

Previous Names

zmp:0000000835 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Shukla-Vernon syndrome. Orthologous to human BCORL1 (BCL6 corepressor like 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bcorl1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Shukla-Vernon syndrome	Alliance	Shukla-Vernon syndrome	301029

Associated With bcorl1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR032365	BCL-6 corepressor, PCGF1 binding domain
Family	IPR047144	BCL-6 corepressor-like
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Homologous_superfamily	IPR038227	PCGF Ub-like fold discriminator superfamily
Repeat	IPR002110	Ankyrin repeat

Domain Details Per Protein

Protein	Length	Ankyrin repeat	Ankyrin repeat-containing domain superfamily	BCL-6 corepressor-like	BCL-6 corepressor, PCGF1 binding domain	PCGF Ub-like fold discriminator superfamily
UniProtKB:A0A8M2BKM1 InterPro	1514
UniProtKB:A0A8M2BKM5 InterPro	1513
UniProtKB:A0A8M1PRS1 InterPro	1510

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	bcorl1-201 (1) Ensembl	Ensembl	6,220 nt	Select Tool ZFIN BLAST
mRNA	bcorl1-202 (1) Ensembl	Ensembl	237 nt	Select Tool ZFIN BLAST
mRNA	bcorl1-203 (1) Ensembl	Ensembl	3,158 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations