Gene

dock10

ID

ZDB-GENE-130530-773

Name

dedicator of cytokinesis 10

Symbol

dock10 Nomenclature History

Previous Names

zmp:0000000770 (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Orthologous to human DOCK10 (dedicator of cytokinesis 10).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dock10 Human Ortholog

No data available

Associated With dock10 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR021816	Dedicator of cytokinesis C/D, N-terminal
Domain	IPR027007	C2 DOCK-type domain
Domain	IPR027357	DOCKER domain
Domain	IPR037809	Dedicator of cytokinesis D, C2 domain
Domain	IPR046769	DOCKER, Lobe A
Domain	IPR046770	DOCKER, Lobe B
Domain	IPR046773	DOCKER, Lobe C
Family	IPR026791	Dedicator of cytokinesis
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR016024	Armadillo-type fold
Homologous_superfamily	IPR035892	C2 domain superfamily
Homologous_superfamily	IPR043161	Dedicator of cytokinesis, C-terminal, lobe A
Homologous_superfamily	IPR043162	Dedicator of cytokinesis, C-terminal, lobe C

Domain Details Per Protein

Protein	Length	Armadillo-type fold	C2 DOCK-type domain	C2 domain superfamily	Dedicator of cytokinesis	Dedicator of cytokinesis C/D, N-terminal	Dedicator of cytokinesis, C-terminal, lobe A	Dedicator of cytokinesis, C-terminal, lobe C	Dedicator of cytokinesis D, C2 domain	DOCKER domain	DOCKER, Lobe A	DOCKER, Lobe B	DOCKER, Lobe C	PH-like domain superfamily	Pleckstrin homology domain
UniProtKB:X1WF60 InterPro	2185
UniProtKB:A0A8M9P713 InterPro	2159
UniProtKB:A0A8M9NYD6 InterPro	2171

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	dock10-201 (1) Ensembl	Ensembl	2,157 nt	Select Tool ZFIN BLAST
mRNA	dock10-202 (1) Ensembl	Ensembl	529 nt	Select Tool
mRNA	dock10-203 (1) Ensembl	Ensembl	9,518 nt	Select Tool
mRNA	dock10-204 (1) Ensembl	Ensembl	748 nt	Select Tool ZFIN BLAST
mRNA	dock10-205 (1) Ensembl	Ensembl	1,416 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations