Gene
gaa2
- ID
- ZDB-GENE-130530-749
- Name
- alpha glucosidase 2
- Symbol
- gaa2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable alpha-glucosidase activity and carbohydrate binding activity. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in glycogen storage disease II. Orthologous to human GAA (alpha glucosidase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR030458 | Glycosyl hydrolases family 31, active site |
| Conserved_site | IPR030459 | Glycosyl hydrolases family 31, conserved site |
| Domain | IPR000322 | Glycoside hydrolase family 31, TIM barrel domain |
| Domain | IPR000519 | P-type trefoil domain |
| Domain | IPR025887 | Glycoside hydrolase family 31, N-terminal domain |
| Domain | IPR048395 | Glycosyl hydrolase family 31, C-terminal domain |
| Homologous_superfamily | IPR011013 | Galactose mutarotase-like domain superfamily |
| Homologous_superfamily | IPR013780 | Glycosyl hydrolase, all-beta |
| Homologous_superfamily | IPR017853 | Glycoside hydrolase superfamily |
| Homologous_superfamily | IPR044913 | P-type trefoil domain superfamily |
Domain Details Per Protein
| Protein | Length | Galactose mutarotase-like domain superfamily | Glycoside hydrolase family 31, N-terminal domain | Glycoside hydrolase family 31, TIM barrel domain | Glycoside hydrolase superfamily | Glycosyl hydrolase, all-beta | Glycosyl hydrolase family 31, C-terminal domain | Glycosyl hydrolases family 31, active site | Glycosyl hydrolases family 31, conserved site | P-type trefoil domain | P-type trefoil domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1RH12
|
956 | ||||||||||
|
UniProtKB:A0A8M3AXU8
|
966 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch73-12o23.1-201
(1)
|
Ensembl | 4,821 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance