Gene

smu1b

ID

ZDB-GENE-130530-635

Name

SMU1 DNA replication regulator and spliceosomal factor b

Symbol

smu1b Nomenclature History

Previous Names

zmp:0000000632 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to be involved in RNA splicing. Predicted to act upstream of or within mRNA splicing, via spliceosome. Predicted to be located in nuclear speck. Predicted to be part of precatalytic spliceosome. Orthologous to human SMU1 (SMU1 DNA replication regulator and spliceosomal factor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With smu1b Human Ortholog

No data available

Associated With smu1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR006594	LIS1 homology motif
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR006595	CTLH, C-terminal LisH motif
Domain	IPR054532	TPL/SMU1, LisH-like dimerisation domain
Family	IPR045184	WD40 repeat-containing protein SMU1
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat

Domain Details Per Protein

Protein	Additional Resources	Length	CTLH, C-terminal LisH motif	G-protein beta WD-40 repeat	LIS1 homology motif	TPL/SMU1, LisH-like dimerisation domain	WD40 repeat	WD40 repeat, conserved site	WD40-repeat-containing domain superfamily	WD40 repeat-containing protein SMU1	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:E7FFQ0	InterPro	539
UniProtKB:A0A8M6YZI5	InterPro	369

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	smu1b-201 (1) Ensembl	Ensembl	2,330 nt	Select Tool ZFIN BLAST
mRNA	smu1b-202 (1) Ensembl	Ensembl	6,402 nt	Select Tool ZFIN BLAST
mRNA	smu1b-203 (1) Ensembl	Ensembl	6,191 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations