Gene

afg3l1

ID
ZDB-GENE-121214-51
Name
AFG3-like AAA ATPase 1
Symbol
afg3l1 Nomenclature History
Previous Names
  • si:ch1073-174d20.2
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have ATP binding activity; metalloendopeptidase activity; and zinc ion binding activity. Predicted to be involved in several processes, including cristae formation; mitochondrial fusion; and mitochondrial protein processing. Predicted to localize to mitochondrial inner membrane.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With afg3l1 Human Ortholog
No data available
Associated With afg3l1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003960 ATPase, AAA-type, conserved site
Domain IPR000642 Peptidase M41
Domain IPR003593 AAA+ ATPase domain
Domain IPR003959 ATPase, AAA-type, core
Domain IPR011546 Peptidase M41, FtsH extracellular
Domain IPR041569 AAA ATPase, AAA+ lid domain
Family IPR005936 ATP-dependent zinc metalloprotease, FtsH
Family IPR050928 ATP-dependent Zinc Metalloprotease
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR037219 Peptidase M41-like
Domain Details Per Protein
Protein Length AAA ATPase, AAA+ lid domain AAA+ ATPase domain ATPase, AAA-type, conserved site ATPase, AAA-type, core ATP-dependent Zinc Metalloprotease ATP-dependent zinc metalloprotease, FtsH Peptidase M41 Peptidase M41, FtsH extracellular Peptidase M41-like P-loop containing nucleoside triphosphate hydrolase
UniProtKB:E7F6D6 751
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:ch1073-174d20.2-201 (1) Ensembl 3,979 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations