Gene
kcnh1b
- ID
- ZDB-GENE-121128-4
- Name
- potassium voltage-gated channel, subfamily H (eag-related), member 1b
- Symbol
- kcnh1b Nomenclature History
- Previous Names
-
- zmp:0000000565 (1)
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Exhibits voltage-gated potassium channel activity. Involved in hindbrain formation and somitogenesis. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Is expressed in gill; nervous system; pleuroperitoneal region; and trunk. Orthologous to human KCNH1 (potassium voltage-gated channel subfamily H member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Stengel et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Stengel et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000014 | PAS domain |
Domain | IPR000595 | Cyclic nucleotide-binding domain |
Domain | IPR000700 | PAS-associated, C-terminal |
Domain | IPR005821 | Ion transport domain |
Family | IPR003938 | Potassium channel, voltage-dependent, EAG/ELK/ERG |
Family | IPR003949 | Potassium channel, voltage-dependent, EAG |
Family | IPR050818 | Voltage-gated potassium channel family H |
Homologous_superfamily | IPR014710 | RmlC-like jelly roll fold |
Homologous_superfamily | IPR018490 | Cyclic nucleotide-binding domain superfamily |
Homologous_superfamily | IPR035965 | PAS domain superfamily |
Repeat | IPR001610 | PAC motif |
Domain Details Per Protein
Protein | Length | Cyclic nucleotide-binding domain | Cyclic nucleotide-binding domain superfamily | Ion transport domain | PAC motif | PAS-associated, C-terminal | PAS domain | PAS domain superfamily | Potassium channel, voltage-dependent, EAG | Potassium channel, voltage-dependent, EAG/ELK/ERG | RmlC-like jelly roll fold | Voltage-gated potassium channel family H |
---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M3AXZ2
|
965 | |||||||||||
UniProtKB:K4EHU2
|
956 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance