Gene
uba7
- ID
- ZDB-GENE-121120-4
- Name
- ubiquitin-like modifier activating enzyme 7
- Symbol
- uba7 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin activating enzyme activity. Predicted to be involved in cellular response to DNA damage stimulus; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within protein modification process. Predicted to be active in cytoplasm and nucleus. Orthologous to human UBA7 (ubiquitin like modifier activating enzyme 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR033127 | Ubiquitin-activating enzyme E1, Cys active site |
| Conserved_site | IPR018074 | Ubiquitin-activating enzyme E1, conserved site |
| Domain | IPR000594 | THIF-type NAD/FAD binding fold |
| Domain | IPR018965 | Ubiquitin-activating enzyme E1, C-terminal |
| Domain | IPR019572 | Ubiquitin-activating enzyme, SCCH domain |
| Domain | IPR032418 | Ubiquitin-activating enzyme E1, FCCH domain |
| Domain | IPR032420 | Ubiquitin-activating enzyme E1, four-helix bundle |
| Family | IPR000011 | Ubiquitin/SUMO-activating enzyme E1-like |
| Family | IPR018075 | Ubiquitin-activating enzyme E1 |
| Family | IPR045886 | ThiF/MoeB/HesA family |
| Homologous_superfamily | IPR035985 | Ubiquitin-activating enzyme |
| Homologous_superfamily | IPR038252 | Ubiquitin-activating enzyme E1, C-terminal domain superfamily |
| Homologous_superfamily | IPR042063 | Ubiquitin-activating enzyme E1, SCCH domain |
| Homologous_superfamily | IPR042302 | Ubiquitin-activating enzyme E1, FCCH domain superfamily |
| Homologous_superfamily | IPR042449 | Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 |
Domain Details Per Protein
| Protein | Length | ThiF/MoeB/HesA family | THIF-type NAD/FAD binding fold | Ubiquitin-activating enzyme | Ubiquitin-activating enzyme E1 | Ubiquitin-activating enzyme E1, conserved site | Ubiquitin-activating enzyme E1, C-terminal | Ubiquitin-activating enzyme E1, C-terminal domain superfamily | Ubiquitin-activating enzyme E1, Cys active site | Ubiquitin-activating enzyme E1, FCCH domain | Ubiquitin-activating enzyme E1, FCCH domain superfamily | Ubiquitin-activating enzyme E1, four-helix bundle | Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 | Ubiquitin-activating enzyme E1, SCCH domain | Ubiquitin-activating enzyme, SCCH domain | Ubiquitin/SUMO-activating enzyme E1-like |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7EYF3
|
1016 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance