Gene
alpk3b
- ID
- ZDB-GENE-121101-3
- Name
- alpha-kinase 3b
- Symbol
- alpk3b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in cardiac muscle cell development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy. Orthologous to human ALPK3 (alpha kinase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cardiomyopathy, familial hypertrophic 27 | 618052 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR004166 | Alpha-type protein kinase, alpha-kinase domain |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Alpha-type protein kinase, alpha-kinase domain | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Protein kinase-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PZ45
|
1934 | ||||||||
|
UniProtKB:A0A8M9PPS8
|
1921 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
alpk3b-201
(1)
|
Ensembl | 6,122 nt |
Interactions and Pathways
No data available
Plasmids
No data available