Gene

acsf3

ID
ZDB-GENE-121026-3
Name
acyl-CoA synthetase family member 3
Symbol
acsf3 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable CoA-ligase activity. Predicted to be involved in fatty acid biosynthetic process. Predicted to act upstream of or within fatty acid metabolic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined malonic and methylmalonic acidemia. Orthologous to human ACSF3 (acyl-CoA synthetase family member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With acsf3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
combined malonic and methylmalonic acidemia Alliance Combined malonic and methylmalonic aciduria 614265
Associated With acsf3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020845 AMP-binding, conserved site
Domain IPR000873 AMP-dependent synthetase/ligase domain
Domain IPR025110 AMP-binding enzyme, C-terminal domain
Homologous_superfamily IPR042099 ANL, N-terminal domain
Homologous_superfamily IPR045851 AMP-binding enzyme, C-terminal domain superfamily
Domain Details Per Protein
Protein Additional Resources Length AMP-binding, conserved site AMP-binding enzyme, C-terminal domain AMP-binding enzyme, C-terminal domain superfamily AMP-dependent synthetase/ligase domain ANL, N-terminal domain
UniProtKB:A0A2R8QA86 InterPro 579
UniProtKB:E7F2S8 InterPro 579
UniProtKB:A0A2R8QFY7 InterPro 579
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations
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