Gene
pdk2a
- ID
- ZDB-GENE-120910-1
- Name
- pyruvate dehydrogenase kinase 2a
- Symbol
- pdk2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in glucose homeostasis and negative regulation of pyruvate dehydrogenase activity. Predicted to localize to mitochondrion. Orthologous to human PDK2 (pyruvate dehydrogenase kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR005467 | Histidine kinase domain |
Domain | IPR018955 | Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal |
Family | IPR039028 | PDK/BCKDK protein kinase |
Homologous_superfamily | IPR036784 | Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily |
Homologous_superfamily | IPR036890 | Histidine kinase/HSP90-like ATPase superfamily |
Domain Details Per Protein
Protein | Length | Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily | Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal | Histidine kinase domain | Histidine kinase/HSP90-like ATPase superfamily | PDK/BCKDK protein kinase |
---|---|---|---|---|---|---|
UniProtKB:A0A8M1Q154
|
409 | |||||
UniProtKB:E7FD62
|
409 |
Interactions and Pathways
No data available
Plasmids
No data available