Gene

znf644b

ID
ZDB-GENE-120214-23
Name
zinc finger protein 644b
Symbol
znf644b Nomenclature History
Previous Names
  • si:ch211-15l16.2
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity. Involved in camera-type eye photoreceptor cell differentiation; neuron cellular homeostasis; and regulation of gene silencing. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in myopia. Is expressed in head; midbrain; optic cup; presumptive retinal pigmented epithelium; and trunk. Orthologous to human ZNF644 (zinc finger protein 644).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Olsen et al., 2016
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from Olsen et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With znf644b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
myopia Alliance Myopia 21, autosomal dominant 614167
Associated With znf644b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Family IPR051643 Transcriptional Regulators with Zinc Finger Domains
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Transcriptional Regulators with Zinc Finger Domains Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:A0A8M2BG18 1235
UniProtKB:A0A8M9Q5E5 1235
UniProtKB:A0A8M9PMS3 1267
UniProtKB:A0A8M9QAA3 1267
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA znf644b-201 (1) Ensembl 10,495 nt
mRNA znf644b-202 (1) Ensembl 6,483 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations