Gene

trpm6

ID
ZDB-GENE-111212-1
Name
transient receptor potential cation channel, subfamily M, member 6
Symbol
trpm6 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have ATP binding activity; cation channel activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cation transport; protein phosphorylation; and protein tetramerization. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in intestinal hypomagnesemia 1 and metal metabolism disorder. Is expressed in several structures, including digestive system; heart; opercular flap; pleuroperitoneal region; and scale. Orthologous to human TRPM6 (transient receptor potential cation channel subfamily M member 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With trpm6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
intestinal hypomagnesemia 1 Alliance Hypomagnesemia 1, intestinal 602014
Associated With trpm6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004166 Alpha-type protein kinase, alpha-kinase domain
Domain IPR005821 Ion transport domain
Domain IPR032415 TRPM, tetramerisation domain
Domain IPR041491 TRPM, SLOG domain
Family IPR050927 Transient receptor potential cation channel M
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR037162 TRPM, tetramerisation domain superfamily
Domain Details Per Protein
Protein Length Alpha-type protein kinase, alpha-kinase domain Ion transport domain Protein kinase-like domain superfamily Transient receptor potential cation channel M TRPM, SLOG domain TRPM, tetramerisation domain TRPM, tetramerisation domain superfamily
UniProtKB:A0A0G2KJE9 1530
UniProtKB:G4WAZ8 1875
UniProtKB:A0A8M9Q2T2 1875
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations