Gene

cbx6b

ID

ZDB-GENE-110613-1

Name

chromobox homolog 6b

Symbol

cbx6b Nomenclature History

Previous Names

si:ch211-260m3.3

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to enable chromatin binding activity and methylated histone binding activity. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in nucleus. Predicted to be part of PRC1 complex. Predicted to be active in chromatin. Is expressed in several structures, including digestive system; eye; heart; pectoral fin bud; and pleuroperitoneal region. Orthologous to human CBX6 (chromobox 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Raby et al., 2020

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Huang et al., 2013
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cbx6b Human Ortholog

No data available

Associated With cbx6b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR023779	Chromo domain, conserved site
Conserved_site	IPR033773	CBX family C-terminal motif
Domain	IPR000953	Chromo/chromo shadow domain
Domain	IPR023780	Chromo domain
Family	IPR001759	Pentraxin-related
Family	IPR052458	Polycomb group PRC1-like complex component
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR016197	Chromo-like domain superfamily

Domain Details Per Protein

Protein	Length	CBX family C-terminal motif	Chromo/chromo shadow domain	Chromo domain	Chromo domain, conserved site	Chromo-like domain superfamily	Concanavalin A-like lectin/glucanase domain superfamily	Pentraxin-related	Polycomb group PRC1-like complex component
UniProtKB:A0A8M9PZU0 InterPro	1058

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	cbx6b-201 (1) Ensembl	Ensembl	1,509 nt	Select Tool ZFIN BLAST
mRNA	cbx6b-202 (1) Ensembl	Ensembl	752 nt	Select Tool ZFIN BLAST
mRNA	cbx6b-203 (1) Ensembl	Ensembl	859 nt	Select Tool ZFIN BLAST
mRNA	cbx6b-204 (1) Ensembl	Ensembl	1,522 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations