Gene
shprh
- ID
- ZDB-GENE-110512-2
- Name
- SNF2 histone linker PHD RING helicase
- Symbol
- shprh Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin protein ligase activity. Predicted to be involved in cellular response to DNA damage stimulus and protein polyubiquitination. Predicted to localize to nucleosome and nucleus. Orthologous to human SHPRH (SNF2 histone linker PHD RING helicase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR000330 | SNF2, N-terminal |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR005818 | Linker histone H1/H5, domain H15 |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR018957 | Zinc finger, C3HC4 RING-type |
| Domain | IPR048686 | E3 ubiquitin-protein ligase SHPRH, first helical domain |
| Domain | IPR048695 | E3 ubiquitin-protein ligase SHPRH, second helical domain |
| Domain | IPR049730 | SNF2/RAD5-like, C-terminal helicase domain |
| Family | IPR052583 | ATP-dependent Helicase/E3 Ubiquitin Ligase |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
| Homologous_superfamily | IPR038718 | SNF2-like, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | ATP-dependent Helicase/E3 Ubiquitin Ligase | E3 ubiquitin-protein ligase SHPRH, first helical domain | E3 ubiquitin-protein ligase SHPRH, second helical domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | Linker histone H1/H5, domain H15 | P-loop containing nucleoside triphosphate hydrolase | SNF2-like, N-terminal domain superfamily | SNF2, N-terminal | SNF2/RAD5-like, C-terminal helicase domain | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily | Zinc finger, C3HC4 RING-type | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q6D1
|
1644 | |||||||||||||||||||
|
UniProtKB:X1WD98
|
1644 | |||||||||||||||||||
|
UniProtKB:A0A8M3AU15
|
1643 | |||||||||||||||||||
|
UniProtKB:A0A8M9Q262
|
1643 |
Interactions and Pathways
No data available
Plasmids
No data available