Gene
npc1l1
- ID
- ZDB-GENE-110510-5
- Name
- NPC1-like 1
- Symbol
- npc1l1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable cholesterol binding activity. Predicted to be involved in cholesterol homeostasis; intestinal cholesterol absorption; and sterol transport. Predicted to be located in endomembrane system and membrane. Predicted to be active in plasma membrane. Is expressed in intestine and liver. Orthologous to human NPC1L1 (NPC1 like intracellular cholesterol transporter 1).
- Genome Resources
-
- Alliance (1)
- Gene:100616532 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | HMGCR/SNAP/NPC1-like, sterol-sensing domain | Niemann-Pick C1, N-terminal | NPC1-like | NPC1, middle luminal domain | Sterol-sensing domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QJ16
|
1411 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance